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Metode Time Discontinuous Galerkin Orde Tinggi Untuk Simulasi Numerik Getaran Paksa Berbasis Pemprograman Berorientasi Obyek
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| Pengarang | : | - |
| Nama Majalah/Jurnal | : | Jurnal Teknologi Industri |
| Volume / Edisi | : | XI (No. 2) |
| Halaman | : | 103-112 |
| Abstrak | : | This paper describes with the formulation, implementation and application of time discontinuous galerkin for solving initial value problem Galerkin weighted residual methods using discontinuous approximations are developed, the formulation of the methods is based on high degree of Lagrange Legendre interpolants in time. The computer programs are written in C++ based on object oriented programming Numerical simulation of forced vibration systems are presented illustrating the performance of the proposed schemes and confirming the analytical results |
Model Penetuan panjang Periode Ketidaktersediaan Fuzzy Untuk Penetapan Tanggal Jatuh Penjadwalan FlowShop
| Pengarang | : | Dewa, Parama Kartika,Ernawati |
| Nama Majalah/Jurnal | : | Jurnal Teknologi Industri |
| Volume / Edisi | : | XI (No. 2) |
| Halaman | : | 93-102 |
| Abstrak | : | Common problem for an industry is to determine the due date. This deal with scheduling theory. Basic model assumes that all machines are always available to process throughout the planning horizon. For particular cases there is machine unavailability in the planning horizon. Previous researches propose due date determination model which accommodate limited machine availability condition in flow shop production system. This model was considered with static period unavailability of machine. This paper propose model to determine period unavailability of machine with fuzzy concept The level of machine breakdown and availability number of operator to repair becomes input for model to determine period unavailability of machine. |
Clinical Implications of Gut-Lung Axis in Systemic Chemotherapy for Lung Cancer
| Pengarang | : | Indry Agatha, Widiya Hari Kurnia, Mirna Nastiti Louqi Machfud, Stella Pangestika, Candra Muhammad Yusuf Hidayatullah, Arya Marganda Simanjuntak |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 127-136 |
| Abstrak | : | Lung cancer incidence continues to increase globally, with an estimated mortality rate of 18% worldwide. Current management strategies focus on early screening, early treatment, and palliative care. However, more fundamental approaches are needed to improve treatment outcomes. The gut-lung axis has emerged as an important factor in lung cancer pathophysiology, as it plays a role in pulmonary immune defense and is influenced by changes in gut and lung microbiota. Alterations in microbial composition have been observed in lung cancer patients and may contribute to disease progression. Systemic chemotherapy, while targeting cancer cells, also exerts systemic effects that may disrupt gut and lung microbiota, leading to dysbiosis. These changes may influence treatment response, immune modulation, and clinical outcomes in lung cancer patients. This narrative review explores the role of the gut-lung axis in lung cancer and examines the impact of systemic chemotherapy on gut and lung microbiota. Understanding the interaction between chemotherapy and the gut-lung axis may provide insight into potential adjuvant strategies to improve treatment effectiveness and patient quality of life. |
Delayed Spleen Bleeding
| Pengarang | : | Juven Luvianto, I Wayan Periadijaya |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 121-126 |
| Abstrak | : | Delayed spleen hemorrhage (DSH) is defined as rupture or hemorrhage of the spleen occurring 48 hours or more after blunt trauma. Although relatively uncommon, DSH is associated with a higher mortality rate compared to acute splenic injury. The interval between the initial traumaand the onset of DSH may range from several days to weeks or even months, and it may also occur following minor trauma. The spleen is a highly vascular organ, making splenic injury a potentially life-threatening condition due to the risk of intra-abdominal hemorrhage. DSH can develop in patients who were previously hemodynamically stable and had no radiological evidence of splenic injury on initial imaging. Diagnosis is often challenging because clinical manifestations may be nonspecific and long time interval since the trauma. Imaging studies, particularly computed tomography, play a crucial role in confirming the diagnosis and assessing the severity of splenic injury. Management of DSH depends on the patient’s hemodynamic status and the grade of the splenic injury, and may include non-operative management, embolization, or surgical intervention. Early recognition is essential to improving clinical awareness, accelerating diagnosis, and reducing morbidity and mortality risks. |
Optimizing Circadian Rhythms Through Physical Activity as an Anti-Aging Strategy
| Pengarang | : | Nitya Indira I Gusti Ayu, Inten Dwi Primayanti I Dewa Ayu |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 117-120 |
| Abstrak | : | Aging is a complex, multifactorial biological process characterized by progressive decline in physiological function and increased vulnerability to chronic diseases. This process is closely associated with circadian rhythm dysfunction, an endogenous 24-hour biological regulatory system that plays a crucial role in maintaining homeostasis through the regulation of metabolism, immune function, and the sleep-wake cycle. Circadian dysregulation not only accompanies aging but may also accelerate degenerative processes and increase the risk of various chronic diseases. Physical activity is recognized as a potent non-photic zeitgeber capable of modulating and strengthening bothcentral and peripheral circadian rhythms. The mechanisms involved include regulation of clock gene expression, modulation of core body temperature, alterations in hormonal, and effects on metabolic pathways and cellular energy sensors. This literature review discusses theinteraction between circadian rhythms, physical activity, and the aging process, and examines how optimization of circadian rhythm through appropriately planned physical activity may contribute as a progressive anti-aging strategy. Such an approach has the potential to supportimproved healthspan and preservation of physiological function with advancing age. |
Myocardial Infarction in Patients with HIV Infection: A Case Report
| Pengarang | : | Adriani Sakina, Fitri Rahmah |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 112-116 |
| Abstrak | : | Introduction: The association of myocardial infarction and HIV infection is influenced by many risk factors, either the specific risk factors of cardiovascular and metabolic disease, or HIV-related risk factors related to the immunologic process and the effects of antiretrovirals (ARV). Case: A 43-year-old man on ARV therapy presented with chest pain as heaviness under the left breastbone and referred to the shoulder to the back for 24 hours. The ECG showed ST-segment elevation in leads II, III, and aVF. The patient underwent intensive cardiac care and receivedaspirin therapy with a loading dose of 160 mg, followed by a maintenance dose of 80 mg daily, clopidogrel therapy with a loading dose of 300 mg, followed by a maintenance dose of 75 mg daily, and intravenous anticoagulant enoxaparin injection therapy, 75 mg twice daily. Thepatient also finally stopped smoking. Discussion: Myocardial infarction in people with HIV is a multifactorial condition influenced by various risk factors, chronic inflammation associated with HIV, endothelial dysfunction, and the effects of certain ARV therapies. The combination of tenofovir-based ARVs and efavirenz has not been shown to increase the risk of myocardial infarction and even has a protective effect on lipid profiles. Conclusion: In general, management of myocardial infarction in HIV-infected patients did not differ from that of general population;one important issue being the drug interaction of ARV with antiplatelet agents and statins. The prognosis of HIV-infected patients who had myocardial infarction did not differ from that of those without. However, acute myocardial infarction recurrence in the HIV-infected population is higher than general population. |
Bilateral Spontaneous Pneumothorax as Manifestation of COVID-19: Case Report
| Pengarang | : | Edgar David Sigarlaki, Nur Chandra Bunawan, Nasya Amalia, Annisa Dian Harlivasari, Cathleen Kenya, Yoni Vanto, Hardijatmo Muljo Nugroho |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 108-111 |
| Abstrak | : | Introduction: Spontaneous pneumothorax occurs when part of the lung collapses and air accumulates in the pleural space. The cause of spontaneous pneumothorax is unclear, but this condition may increase the risk of death, particularly if it progresses to tension pneumothorax.COVID-19 is primarily a respiratory disease and may present with various pulmonary manifestations, including rare and severe complications. Case: A 48-year-old woman presented with dyspnea, fever, cough, nausea, and fatigue. Initial rapid antibody testing for SARS-CoV-2 wasnegative. Chest radiograph demonstrated an avascular area in the right lateral hemithorax with medial lung collapse, consistent with right spontaneous pneumothorax. Oxygen therapy and chest tube insertion were performed. Follow up chest x-ray showed resolution of the rightpneumothorax, however, a new pneumothorax developed on the left side. Nasopharyngeal and oropharyngeal swab testing for SARS-CoV-2 was reported positive a few days later, after the patient had died. Discussion: The occurrence of bilateral spontaneous pneumothoraxin this patient suggests lung involvement related to COVID-19 infection. Recognition of atypical pulmonary manifestations is essential, particularly when initial screening tests are negative. Conclusion: COVID-19 can manifest as spontaneous pneumothorax, including bilateral involvement. Early recognition is important to reduce morbidity and mortality. |
Onychomadesis as a Rare Complication of Hand, Foot, and Mouth Disease: Case Report
| Pengarang | : | Riana Suwarni, Anjar Nuryanto |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 104-107 |
| Abstrak | : | Introduction: Onychomadesis is a rare nail disorder characterized by the separation of the nail plate from the nail matrix, which may result in nail shedding. It has been reported as a late complication of hand, foot, and mouth disease (HFMD), a common viral infection in childrenthat is usually self-limited but may present with various complications. Case: A 4-year-old boy had developed whitish transverse lines on his fingernails and toenails, followed by separation of the nail from the nail matrix. Two months prior to the nail changes, the patient experiencedfever accompanied by papulovesicular rashes around the mouth, hands, and feet, as well as aphthous lesions in the oral cavity consistent with HFMD infection. At the time of the nail involvement, there was no pain, inflammation, or signs of secondary infection. Discussion: Based on the clinical history and physical findings, a diagnosis of onychomadesis as a late complication of HFMD was established. Onychomadesis is known to occur weeks to months after HFMD and is generally self-limited without the need for specific therapy. Conclusion: Onychomadesismay occur as a late complication of HFMD in children. The condition is benign, does not require special treatment, and is expected to resolve completely within 6 weeks. |
Recurrent Malaria: Case Report
| Pengarang | : | Anindya Dwitiya Putri, Nella Rossiyah, Karlina Sari Sujana, Suvianto Hendri Lesmana |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 53 (No. 2) |
| Halaman | : | 99-103 |
| Abstrak | : | Introduction: Residents in malaria-endemic areas may experience more than 1 episode of malaria even in 1 season. Case: A 29-year-old male with fluctuating fever for 3 days accompanied by chills. The patient had just returned from Papua about 3 weeks before. The patient has worked in Papua for 1 year and has had 5 episodes of malaria: 3 falciparum malaria and 2 vivax malaria. Two months before this current complaint, the patient was taking DHP and primaquine. The patient did not take any malaria prevention drugs before leaving for Papua. Atinitial examination, the temperature was 38.6oC with leukocytosis (13,580/μL). Peripheral blood malaria examination found Plasmodium vivax parasites, stages: trophozoite and gametocyte. Patients were given DHP therapy (dihydroartemisinin 40 mg + piperaquine phosphate 320 mg) 4 times a day for 3 days and primaquine 15 mg once a day. Discussion: On the second day of treatment or the fourth day since symptom onset, the clinical condition began to improve. On the fourth day of treatment or the sixth day since symptom onset, the patient had no complaints, and vital signs and physical examination were within normal limits. The patient was discharged after continuing primaquine 15 mg for the next 11 days. Conclusion: DHP therapy (dihydroartemisinin 40 mg + piperaquine phosphate 320 mg) 4 times a day for 3 days and primaquine once at 15 mg results in a radical curative effect. |
Reimagining physics/education
| Pengarang | : | Deepak Iyer |
| Nama Majalah/Jurnal | : | The Physics Teacher |
| Volume / Edisi | : | 60 (No. 6) |
| Halaman | : | 518–519 |
| Abstrak | : | In our May 2021 opening article for the column Just Physics?, we posed two questions: What does it mean to think beyond just physics, specifically, to think about physics and physics education in the context of the social and political realities of the world? What constitutes just physics, i.e., what does physics for justice look like? |