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PASANG-SURUT HUBUNGAN INDONESIA-SOVIET

Pengarang : -
Nama Majalah/Jurnal : Analisa
Volume / Edisi : XIII-12, DESEMBER (No. 12)
Halaman : 901-907
Abstrak : -

HUBUNGAN BILATERAL ANTARA INDONESIA DAN UNI SOVIET: DIMENSI DAN PROSPEK

Pengarang : Harsja W.Bachtiar
Nama Majalah/Jurnal : Analisa
Volume / Edisi : XIII-12, DESEMBER (No. 12)
Halaman : 889-900
Abstrak : -

Carbamazepine-Induced Stevens-Johnson Syndrome in an Epilepsy Patient: Case Report

Pengarang : Charity Harlim, Kelvin Kelvin, Agung Triana Hartati
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 40-43
Abstrak : Introduction: As a first-line antiepileptic drug for partial and tonic-clonic seizures, carbamazepine requires long-term use. This drug carries a risk of Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN) reaction. Case: A 23-year-old woman with a history of seizures had reddish rashes on the face, neck, chest, back, and left and right upper extremities covering 10% of the body surface area (BSA) after taking carbamazepine 200 mg twice a day for her seizures. Discussion: The patient was given methylprednisolone 16 mg tablets twicea day, IV diphenhydramine twice a day, and other symptomatic drugs. After 9 days, the patient was discharged with phenytoin 100 mg tablets twice a day as a substitute for carbamazepine. Early treatment with high-dose systemic steroids provides benefits of rapid recovery,especially in SJS patients where skin damage is not too extensive and can be restored by the anti-inflammatory effects of steroids. The main treatment of SJS/TEN is early recognition and immediate discontinuation of the drug. Conclusion: Carbamazepine is often a risk factor forSJS, thus an alternative treatment is needed.

Electrolyte Imbalance–Induced Brugada Phenocopy: A Complex Intersection of Hyperkalemia, Hyponatremia,and Acidosis – Case Report

Pengarang : dr. Yuddy Imowanto, Sp.EM, KEC, FICEP, dr.Taufiq Abdullah, Sp.EM, KTOX, FICEP, Sri Wahyuni
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 35-39
Abstrak : Introduction: Brugada phenocopies (BrP), which are different from real congenital Brugada syndrome (BrS), are clinical entities with different etiology. BrP can manifest in a range of conditions, such as metabolic disturbances like hypokalemia, hyperkalemia, hypophosphatemia, hyponatremia, and acute toxicity. Case: Brugada phenocopy was observed in the ECG of a 68-year-old male, resolved following the correction of hyperkalemia, hyponatremia, and acidosis. The patient presented with septic shock and multiorgan dysfunction, which contributed to severe electrolyte imbalance and metabolic derangements. Despite initial stabilization and improvement in ECG findings after targeted correction, the patient ultimately developed progressive clinical deterioration. Discussion: Recognizing BrP helps identify reversible causes of the ECG changes, allowing for proper treatment and prevention of complications. This case highlights the importance of evaluating underlying metabolic and systemic conditions when encountering Brugada-like ECG patterns. Conclusion: Brugada phenocopy can occur in hyperkalemia and hyponatremia in an acidosis state. Clinicians should consider comprehensive clinical assessment, laboratory evaluation, and ECG monitoring to distinguish BrP from congenital BrS, especially in critically ill patients.

Type II Acute Respiratory Failure in Patients with Chronic Obstructive Pulmonary Disease (COPD) Acute Exacerbation Treated with High Flow Nasal Cannula (HFNC): Case Report

Pengarang : Abdi Malik Rahardjo, Mokhammad Mukhlis
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 30-34
Abstrak : Introduction: Acute respiratory failure is a condition seen in respiratory system failure to supply gas exchange, oxygenation, and elimination of carbon dioxide (CO2) processes that occurs in minutes or hours. Case: A 57-year-old male came to the emergency room with complaints of shortness of breath since 5 days ago, worsened during light activities. The patient also complained of worsening cough since 5 days ago, accompanied by thick yellowish-white phlegm. History of smoking 12 sticks/day since the age of 20 years and quit 5 years ago. Diagnosis was acute respiratory failure type II and the cause was chronic obstructive pulmonary disease (COPD) acute exacerbation. The management is high flow nasal cannula (HFNC) with FiO2 80%, because HFNC has an additional heating and humidification system that makes it more comfortable. Discussion: Alveolar hypoventilation and increased minute ventilation in COPD patients may carry a type II acute respiratory failure risk. Conclusion: Type II acute respiratory failure commonly occurs in patients with chronic respiratory diseases such as COPD. High flow nasal cannula (HFNC) oxygen therapy may be the best option.

Instant Tempeh Porridge and Commercial Diabetic Preparation for Patients with Type 2 Diabetes Mellitus, Caput Pancreas Cancer, and Hypoalbuminemia: Case Study.

Pengarang : Ni Putu Destriani Devi, Ni Putu Elsa Herawati
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 25-29
Abstrak : Introduction: Patients with diabetes mellitus and caput pancreas cancer generally experience decreased food intake due to gastrointestinal complaints, such as abdominal pain, nausea, vomiting, and feeling full. This condition can be managed by providing small portions of nutrientdense and easily digested food to prevent decline in nutritional status and patient condition. Case: A 58-year-old male with right upper abdominal pain, fever, and white stools was treated for caput pancreas cancer and hypoalbuminemia. History of type 2 diabetes mellitus for 2years and biliary stent placement. Food intake at home is < 25% of the requirement. The patient is underweight with body mass index (BMI) 16 kg/m2, hypoalbuminemia (2.6 g/dL), and hyperglycemia (random glucose 220 mg/dL). This nutritional intervention aims to gradually optimizefood intake (target > 80% requirement) in 5 days, with easily digestible and low glycemic index food in the form of modification of instant tempeh porridge and commercial diabetic preparation in small portion. Discussion: The nutritional intervention is acceptable to the patient.Conclusion: Modified instant tempeh porridge and commercial diabetic preparation can increase patient intake with good acceptance and improve gastrointestinal tolerance.

Bibliometric Analysis of Telemedicine Service Utilisation in Obstetrics and Gynaecology

Pengarang : Widi Fatma, Penggalih Mahardika Herlambang, Rani Tiyas Budiyanti
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 19-24
Abstrak : Introduction: Telemedicine in health services has various advantages, such as cost flexibility and time efficiency. This research aims to map research related to the application of telemedicine in obstetrics and gynecology. Methods: This study is a quantitative, descriptiveanalytical research using bibliometric analysis of articles published in the Scopus database from 2014 to 2024. Results: We obtained 36 articles on the application of telemedicine in obstetrics and gynecology, with a fluctuating number each year. The country with the most affiliated researchers was the United States, with 19 publications. Most articles were research articles (80.6%) and published in medical journals (67.3%). Conclusion: Based on the study’s results, 4 countries have conducted collaborative research, and 3 keyword mapping clusters relate to the application of telemedicine in obstetrics and gynecology. Cross-sector and cross-border collaboration is necessary, especially in ethical and legal aspects that enable the implementation of cross-border or cross-continental telemedicine. Further research and literature review are needed to assess further the procedures, benefits, and barriers to implementing telemedicine services in obstetrics and gynecology.

The Effect of Smoking on Matrix Metalloproteinase-9 (MMP-9) Expression and Its Relationship with Chronic Obstructive Pulmonary Disease

Pengarang : Oki Nugraha Putra, Rantie Queenza Anabella, Istiara Nafida In’ami, Akbar Yuniar Nur Hasibullah Ma, Ryo Wahyu Purwanto
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 12-18
Abstrak : Introduction: Cigarette smoke can induce the expression of matrix metalloproteinase-9 (MMP-9) and is associated with COPD. This review aims to assess the impact of cigarette smoke on MMP-9 expression and its association with COPD. Methods: This study is a scoping review using articles analyzing the impact of cigarette smoke on MMP-9 levels in COPD patients from the PubMed and Google Scholar databases. A total of 11 articles that met the inclusion criteria were used in this review, of which 6 studies used serum or plasma, 1 study used bronchoalveolar lavage (BAL), and 4 studies used sputum samples to measure MMP-9 levels. Results: Overall, MMP-9 levels were found to be significantly greater in COPD patients who smoked compared to non-smoking COPD patients and healthy individuals. MMP-9 levels increased with increasing severity of COPD. MMP-9 levels correlated with the smoking index. Conclusion: More cigarette consumption will further increase MMP-9 levels. Smoking increases MMP-9 expression and is associated with COPD.

The Relationship between Interleukin 6 (IL-6) Levels and Disease Activity (SLEDAI-2K) and Manifestations of Renal and Non-Renal Damage in Patients with Systemic Lupus Erythematosus

Pengarang : Yesanopa Sianturi, Deske Muhadi Rangkuti, Andi Raga Ginting
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 6-11
Abstrak : Introduction: Systemic lupus erythematosus (SLE) is a chronic, heterogeneous, and complex autoimmune disease. Several studies have linked IL-6 levels and SLE. This study sought to investigate the relationship between IL-6 levels and degree of disease activity and manifestations of renal-non-renal damage in SLE. Methods: A retrospective cross-sectional study of 67 SLE patients based on the SLICC 2012/ACR EULAR 2019 criteria for at least 6 months at the Rheumatology Polyclinic of AM General Hospital, Medan from June to August 2023 who met the inclusion and exclusion criteria. Assessment of renal-non-renal damage used the SLICC DamageIndex-SDI score and the degree of disease activity was measured with SLEDAI-2K. Results: The highest median IL-6 level of 87.32 pg/mL was found in the remission group, while the lowest median IL-6 level of 46.05 pg/mL was found in patients with mild disease. No significant relationship between IL-6 levels and the degree of SLE disease activity (p = 0.158). The median interleukin-6 value in the group of subjects with renal damage was 71.95 pg/mL, while in the group of subjects with non-renal damage it was 53.05 pg/mL. No correlation was found between IL-6 levels and disease activity (p = 0.158), but there was a significant correlation between IL-6 levelsand renal damage (p = 0.045). Conclusion: No relationship between IL-6 levels and the degree of disease activity (p = 0.158), but a significant relationship between IL-6 levels and renal damage (p = 0.045).

The Relationship between Extroverted and Introverted Personality Types and Academic Procrastination in Medical Student

Pengarang : Putri Zalika Laila Mardiah Kesuma, Ratika Febriani, Trisnawati Mundijo , Adelia Ramadhani
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 53 (No. 1)
Halaman : 1-5
Abstrak : Abstrak tidak tersedia.
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