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Kombinasi Krioterapi dan KOH 5% untuk Terapi Kondiloma Akuminata Raksasa dengan Infeksi HIV

Pengarang : Rini Hastuti, Etty Farida Mustifah, Endra Yustin Ellistasari
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 524-527
Abstrak : Giant condyloma acuminata also known as Buschke-Lowenstein tumor is a tumor caused by human papillomavirus (HPV) infection in anorectal area and external genitalia with diameter more than 2.5 cm. Case.A 32 year old homosexual male had multiplying and growing lumps since two months. Patient was diagnosed HIV since 2 years ago. A combination therapy with cryotherapy and KOH 5% solution resulted in clinical improvement. Discussion.Combination therapy may be an option for giant condyloma acuminata with complications or if single therapy does not provide clinical improvement.

Osteoporosis dan Terapi Bisfosfonat

Pengarang : Sherly Desnita Savio
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 519-522
Abstrak : Osteoporosis is a common problem found in daily practice in Indonesia. Osteoporosis is characterized by the decline in bone mineral density (BMD). Risk factors of osteoporosis are family history of osteoporosis, low calcium diet, smoking, overconsumption of alcohol and caffeine, long term steroid usage, and inadequate physical activity. DXA examination for screening and diagnosis is suggested for high risk group. The complications of osteoporosis are vertebral, non-vertebral, and hip fractures. On of osteoporosis therapy is bisphosphonate, especially nitrogen containing bisphosphonates (alendronate, risedronate, ibandronate, zolendronate).

Association between Anemia and First-time Febrile Seizure: A Case Control Study

Pengarang : Handoyo
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 514-517
Abstrak : Febrile seizure is the most frequent neurological disorder in childhood. Some studies report association between anemia and febrile seizure. Even though anemia is highly prevalent in Indonesia, only one study assessed this association. Objective.To compare the hemoglobin level in children with febrile seizure and febrile children without seizure, and to assess the relationship between anemia and febrile seizure. Method.This retrospective case control study used medical record of febrile children aged 6 months to 3 years old hospitalized at Landak General Hospital from May 2016 to April 2017. Hemoglobin level from first blood workup then compared between fifty children with first-time febrile seizure (case group) and a hundred febrile children without seizure (control group). Results.Hemoglobin level was lower in case group compared to control group (p =0.000). Children with febrile seizure were more likely to be anemic compared to febrile children without seizure [OR 6.73 with 95% CI 3.18 to 14.26]. Conclusion.There is significant difference of mean hemoglobin among children with febrile seizure compared to febrile children without seizure. Children with febrile seizure were six times more likely to have anemia.

Modalitas Terapi Topikal Vitiligo

Pengarang : Rina Diana, Nurrachmat Mulianto
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 508-513
Abstrak : Vitiligo has potential psychosocial impact on patients. There is currently no therapy to treat vitiligo, but many options are available to treat vitiligo lesions. No single therapy can produce good results in all patients; many treatment options are topical treatments, oral treatments, light therapy, surgical therapy, psychological therapy, and complementary therapies. Increasing research and knowledge on vitiligo patomechanism including relation with oxidative stress, skin blood flow, or a cytokine-mediated mechanisms neuropeptides lead to newly developed topical agents to induce pigmentation.

Profil Respons Glukosa Darah dan Tingkat Rasa Kenyang setelah Pemberian Diabetasol® Dibandingkan Makanan Padat Gizi Terkontrol pada Pasien Diabetes Melitus tipe 2

Pengarang : Fatimah Eliana, Iwan Surjadi Handoko, Fransisca Diah Ambarwati, Arini Setiawati
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 499-506
Abstrak : The purpose of this study was to determine the stability of daily blood glucose level, satiety level, and safety after using Diabetasol® in comparison with controlled nutrition solid food. Diabetasol® is low glycemic index foods contained of isomaltulose, resistant dextrin, and inulin. This study is a preliminary, prospective, randomized, open-ended study, and involving 30 male and female type 2 DM subjects. Blood glucose was measured with continuous glucose monitoring within 48 hours after every visit. The satiety level was measured with satiety quotient questionnaire with visual analog scale (VAS) at interval of 0, 15, 30, 60, and 120 minutes. The evaluation of side effects was based on the occurrence of hypoglycemia and digestive problems during the treatment period. Eventhough not stastistically significant, Diabetasol® leads to decreased glycemic response and longer satiety compared to controlled nutrition solid foods, with no serious side effects.

Incidence of Electrolyte Disturbance after TURP Procedure

Pengarang : Daniel Mahendra Krisna, Akhada Maulana
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 495-498
Abstrak : Trans Urethral Resection of the Prostate (TURP) as a gold standard treatment for benign prostatic hyperplasia (BPH) is performed with fluid irrigation that may cause electrolyte disturbance due to excessive fluid absorption; and may lead to increased mortality. This study is to determine the incidence of electrolyte disturbances and risk factors in TURP procedure. Materials&Methods.A descriptive retrospective study was conducted at Bhayangkara Hospital Mataram in January 2014-January 2016. The subjects were all BPH patients who underwent TURP surgery. Data were retrieved from medical records. All TURP procedures used distilled water as irrigation fluid. Presurgery and postsurgery electrolyte level, digital rectal grading and weight of resection tissue were recorded. Deranged electrolyte was defined as presence of any or both serum sodium < 130 or > 145 mmol/L and serum potassium <3,5 or > 5,5 mmol/L. Student’s T-test was applied to determine significant change between pre and post surgery variables. Results. Of 32 subjects, the mean age was 63.39 years and the mean weight of resected tissue was 63.03 grams. Sodium, potassium, chloride, and hemoglobin level were decreased post surgery (mean reduction 2.00, p = 0.000; 0.25, p = 0.000 ; 27.81, p = 0.021;1.050, p = 0.025, respectively). In 10 subjects, only significant decreased serum chloride and hemoglobin were found (mean reduction 4.5, p = 0.017; 1.46, p = 0.048, respectively). Sodium and potassium serum level were significantly decreased in non deranged electrolyte group (mean reduction 1.8, p = 0.01; 0.27, p = 0.00, respectively). No significant correlation between electrolyte imbalance with age and digital rectal examination grading. Conclusion.Electrolyte serum levels were significantly decreased after TURP procedure.

Hubungan Pemberian Air Susu Ibu dengan Kejadian Kanker Payudara di Rumah Sakit Umum Daerah dr. Zainoel Abidin, Banda Aceh

Pengarang : M. Riswan, Iffah Munawarah
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 491-494
Abstrak : Risk factors of breast cancer are obesity, age of first delivery, breastfeeding, lifestyle, age of menarche, and age of menopause. The aim of this study was to observe the relationship between breastfeeding and breast cancer incidence in dr. Zainoel Abidin Hospital Banda Aceh. Method.A case-control study with accidental sampling on 64 women. Data were collected using questionnaire. Result.Among 32 breast cancer patients, 21 patients did not breastfeed. And among 32 control patients, only 2 patients did not breastfeed. Bivariate analysis using chi square demonstrated significant result p=0,000 (p ≤0,05). Conclusion.There is a significant correlation between breastfeeding and incidence of breast cancer.

Korelasi Kadar Asam Urat dengan Derajat Keganasan Kanker Kolorektal

Pengarang : Subandrate, Safyudin, Ella Amalia, Dwi Indira Setyorini
Nama Majalah/Jurnal : CDK Cermin dunia kedokteran
Volume / Edisi : 45 (No. 7)
Halaman : 487-489
Abstrak : Hyperuricemiain cancer patients increases mortality, especially in advanced phase. Methods: An observational analytic correlative study with cross-sectionaldesign on correlation between uric acid level and cancer stage incolorectalcancer patients. Subjects were 35 colorectal cancer patient, which are15 male and 20 female colorectalcancer patients treated at RSUP Mohammad Hoesin(RSMH). Stage ofcolorectalcancer based onhistopathologyexamination in Anatomy Pathology Laboratory of RSMH/Medical Faculty of Sriwijaya University, Palembang. Serum uric acid level was measured in Biochemistry Laboratory of Medical Faculty of Sriwijaya University. Results: The cancer stage of the patients were stage II (17.1%), stage III(48.6%), and stage IV(34.3%). The mean uric acid levels were 11.8±3.5 mg/dL. Approximately 88.6% of colorectal cancer patients havehyperuricemia. The mean level of uric acid in patients with earlystage colorectalcancer was 10.6 mg/dL, in patients with end-stagecolorectalcancer was 12.3 mg/dL. The correlation between uric acid levels andcolorectalcancer stage was very weak (r=0.072) and was not significant (p=0.647). C onclusion: Hyperuricemiaoccurs in almost all colorectalcancer patients. Uric acid level did not correlate withcolorectalcancer stage.

“Go Easy on Me!” Supervisor Discretion in Target Setting after Managerial Turnover

Pengarang : Mathilde Verschaeve
Nama Majalah/Jurnal : Journal of Management Accounting Research
Volume / Edisi : 37 (No. 3)
Halaman : 121-148
Abstrak : This paper examines supervisors’ target setting decisions following managerial turnover, an event largely overlooked in prior studies. Specifically, we test whether regional supervisors use discretion to assign different target levels to new managers compared to those who remain in their business unit. Moreover, we investigate whether the use of past performance and peer performance information in supervisors’ target revisions is sensitive to managerial turnover. Using field data from 113 nursing homes of a large elderly care provider over a three-year period, we provide evidence that supervisors assign relatively lower targets to new managers. Additionally, our results show that, overall, supervisors rely on past and peer performance information to a similar extent when revising targets for new managers, with a more lenient approach if new managers underperform. Our findings suggest that current knowledge about target setting may be incomplete, as supervisors may treat new managers differently. Data Availability: All data are proprietary and protected by a nondisclosure agreement.

Because I Care: The Effect of Value Congruence and Compensation Scheme on Target Setting in Social Mission Organizations

Pengarang : Wioleta Olczak
Nama Majalah/Jurnal : Journal of Management Accounting Research
Volume / Edisi : 37 (No. 3)
Halaman : 103-120
Abstrak : Many organizations, including for-profit firms, seek to support a social mission. This study experimentally examines how superiors’ value congruence and compensation scheme affect superiors’ target-setting decisions in social mission organizations. We predict and find that more value-congruent superiors set higher targets for their subordinates than less value-congruent superiors to motivate their subordinates to advance the organization’s social mission. We also find that superiors set higher targets for their subordinates when compensated with performance-based pay rather than a fixed wage. We highlight the importance of superiors’ value congruence with the organization’s social initiatives and compensation scheme on their target-setting decisions. Organizations with social initiatives or that are apt to adopt such initiatives should consider our findings when developing formal controls, as superiors’ value congruence with the social mission and their compensation structure can affect the targets they set for their subordinates. Data Availability: Data are available from the authors upon request. JEL Classifications: M52.
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