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| Pengarang | : | Elvira, Victor Nugroho Wijaya |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 3) |
| Halaman | : | 192-196 |
| Abstrak | : | Dry eye disease (DED) is a multifactorial disease of the tears and ocular surface resulting in dyscomfort, visual disturbance, and tear film instability with potential ocular surface damage. The world prevalence is 5-34 %, its incidence increases significantly with age. DED is classified to aqueous deficient dry eye (ADDE) and evaporate dry eye (EDE). Its symptom have been associated with reduced quality of life, increased depressive symptoms, and mood disorders. |
Funduskopi untuk Prognosis Preeklampsia
| Pengarang | : | Ferdy Iskandar, Laura Agnestasia Djunaedi, Angela Shinta Dewi Amita, Sigit Pradono Diptoadi |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 3) |
| Halaman | : | 187-190 |
| Abstrak | : | Hypertension in pregnancy is a health problem since it causes more than 25% of maternal deaths in Indonesia in 2013. In preeclampsia – type of hypertension in pregnancy – there are endothelial dysfunctions in various organs, including eyes. The most common consequences are general vasospasms with plasma leakage causing retinal ischemia leading to permanent damage. There is a linear correlation between Keith-Wagener-Barker classification and probability of death and blindness. Funduscopy can be used as a supplementary examination to help decide the best management and may be an objective tool for estimating prognosis of mother as well as fetal status. |
Pengaruh Protein RPGRIP1L pada Pembentukan Silia Primer sebagai Kandidat Target Terapi Gen Penyakit Siliopati
| Pengarang | : | Ivanna Williantarra |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 3) |
| Halaman | : | 181-185 |
| Abstrak | : | Primary cilia, which has been long considered as a vestigial organelle of little functional importance, is now known as a coordination hub for many signal transduction pathways. Two worst clinical manifestations of ciliopathies are the Meckel (MKS) and Joubert (JBTS) syndrome; Both are caused by the absence of RPGRIP1L protein at the transition zone of primary cilia. This research aims to check the role of RPGRIP1L in ciliogenesis. The effect of RPGRIP1L knockdown towards (1) ciliogenesis frequency, (2) Hedgehog signaling protein expression and (3) localization of other primary cilia proteins were checked using qRT-PCR and immunostaining techniques. It was found that knockdown of RPGRIP1L has caused a 46% reduction of ciliogenesis frequency. The reduction is not due to a lower expression of primary cilia protein, but mis-localization of the proteins; only the proteins which are involved in the early phase of ciliogenesis were correctly localized after RPGRIP1L knockdown, indicating the anchoring function of RPGRIP1L. Moreover, despite the removal of CP110 by TTBK2, the axoneme was not elongated in the absence of RPGRIP1L. |
Calcific Uremic Arteriolopathy pada End-stage Renal Disease
| Pengarang | : | Iraky Mardya Rakhmadhan |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 3) |
| Halaman | : | 177-180 |
| Abstrak | : | Calcific uremic arteriolopathy (CUA) is one of many complications of end-stage renal disease (ESRD), causing high morbidity and mortality. Several risk factors are female gender, diabetes mellitus, hyperphosphatemia, ESRD, mineral and bone disorders, obesity, warfarin, and Caucasian. The gold standard for diagnosis is pathognomonic findings in histological skin examination. Treatment requires multidisciplinary approach involving general measures, optimal wound management, correction of biochemical abnormalities, use of sodium thiosulfate, and other potential therapeutic options such as bisphosphonate, low-molecular-weight heparin, and thrombolytic agents. CUA is potentially fatal, but early diagnosis and optimal treatment can significantly improve outcomes. |
Kejadian Mual Muntah Pasca-Laparatomi (PONV) setelah Pemberian Granisetron Dibandingkan setelah Pemberian Kombinasi Ondansetron - Deksametason
| Pengarang | : | Mulyo Hadi Sudjito, Mulyata, Titik Setyawati |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 3) |
| Halaman | : | 172-175 |
| Abstrak | : | Post operative nausea and vomiting (PONV) is usually experienced after laparatomy with general anesthesia. Methods: A single blind experimental design; 58 subject underwent laparatomy with general anesthesia were randomly divided into 2 groups. Group I received 1 mg granisetron, 30 to 60 minutes before the end of surgery, and group II received 8 mg dexamethasone before anesthesia induction and were given 4 mg ondansetron, 30 to 60 minutes before the end of surgery. All patients were observed for PONV until 24 hours post surgery. Result: In group I PONV could be prevented in 72,4% subject whereas in group II PONV could be prevented in 79,3% subject. Conclusion: No significant difference of efficacy between 4 mg ondansetron and 8 mg dexamethasone, compared to 1 mg granisetron in preventing post laparatomy PONV. |
KL-6/MUC-1 sebagai Penanda Penyakit Paru Interstisial
| Pengarang | : | Juliani Dewi |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 1) |
| Halaman | : | 67-70 |
| Abstrak | : | nterstitial lung diseases are marked by inflammation and fibrosis in the interstitium, a damage and/or regeneration of type II pneumocytes. HCRT (high resolution computed tomography), bronchoscopy, and/or invasive lung biopsy are needed for diagnosis. Krebs Von De Lungen-6 (KL-6), a mucinous, 200 kD molecule weight glycoproteins, secreted by a type II pneumocytes and bronchiolar epithel cells is very promising as a potential and less invasive marker for this interstitial lung diseases. |
Peran Aerosol M. tuberculosis pada Penyebaran Infeksi Tuberkulosis
| Pengarang | : | Gina Amanda |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 1) |
| Halaman | : | 62-65 |
| Abstrak | : | Tuberculosis is an airborne transmitted disease. Droplet coughed by tuberculosis patients may infect other individuals. Examination for acid-fast bacilli from sputum smear has not been able to assess the M. tuberculosis transmissibility. Cough aerosol test for M. tuberculosis may be used to assess the transmission potential of tuberculosis patients to their contacts. |
Paradigma Baru Tuberkulosis pada Era Sustainable Development Goals (SDGs) dan Implikasinya di Indonesia
| Pengarang | : | Anthony Christanto |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 1) |
| Halaman | : | 57-60 |
| Abstrak | : | The era of Millennium Development Goals (MDGs) had ended in 2015 and being substituted with the Sustained Development Goals (SDGs). One of the points of MDGs is TB control, which forms the base of STOP TB program, adopted by many countries including Indonesia. In the SDGs era, STOP TB is substituted by END TB program. Despite the country’s ongoing TB control program stated in the newest national TB control guidelines in 2014, integration with the END TB program should be more encouraged to ensure optimal achievement in the TB control in the SDGs era according to the goals of END TB. |
Thirdhand Tobacco Smoke
| Pengarang | : | Oktavianus Marciano |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 1) |
| Halaman | : | 52-55 |
| Abstrak | : | obacco smoke is harmful to both smoker and non-smoker’s health. Smoke exposure for non-smokers continued in the forms of thirdhand smoke (THS). THS is tobacco smoke residue that sticks to surfaces and can persist for a long period. The components of THS can act as a health hazard. Oktavianus Marciano. Thirdhand Tobacco Smoke. |
Video Assisted Thoracoscopy Surgery (VATS) as Minimal Invasive Approach for Thymoma with Myasthenia Gravis in Gatot Soebroto Central Army Hospital: A Case Report
| Pengarang | : | Febyan, Joni Indah Sari, Sri Handawati Wijaya, Andreas Andri Lensoen |
| Nama Majalah/Jurnal | : | CDK Cermin dunia kedokteran |
| Volume / Edisi | : | 45 (No. 1) |
| Halaman | : | 39-41 |
| Abstrak | : | Mediastinal thymoma is rare, although it is the most common anterior mediastinal mass. It tends to grow slowly and benign, but still potentially malignant. Surgery is the mainstay of treatment. The procedure of choice is still standard or partial sternotomy thymomectomy. Video Assisted Thoracoscopic Surgery (VATS) to mediastinal and lung tumor has shown promising result. The potential advantages of this approach compared to sternotomy include better cosmetic, less postoperative pain, shorter length of stay, earlier return to daily activities, less bleeding and fewer other complication. |